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Depart From

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San Diego, California, United States

San Diego is a vacationer's paradise, with year-round temperatures in the seventies and near-constant sunshine. One of America's most family-friendly cities, San Diego is home to LEGOLAND, the New Children's Museum, and the famous San Diego Zoo. Sunbathers and surfers are guaranteed to find their perfect beach, and foodies find delights in artisanal breweries, local bistros, and gourmet restaurants. From the Broadway excitement of La Jolla Playhouse to the European feel of Little Italy to the nouveau-chic of the Gaslamp Quarter, San Diego has something for everyone.

Cruise Holidays Departing From San Diego, California, United States

108 results Found

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
1 / 0
Serenade of the Seas

3 Night Ensenada Cruise

Start:

San Diego, California

End:

San Diego, California

No Port Available

View Full Itinerary

Days:

4

Depart:

15 October 2026

Return:

18 October 2026

Royal Caribbean International

Inside from:

£266

 PP

Outside from:

£288

 PP

Balcony from:

£326

 PP

Cruise & Flights from:

£1,414

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
1 / 0
Serenade of the Seas

7 Night Ensenada, Cabo & Mazatlan Cruise

Start:

San Diego, California

End:

San Diego, California

No Port Available

View Full Itinerary

Days:

8

Depart:

1 November 2026

Return:

8 November 2026

Royal Caribbean International

Outside from:

£399

 PP

Inside from:

£422

 PP

Balcony from:

£519

 PP

Cruise & Flights from:

£1,469

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
1 / 0
Serenade of the Seas

7 Night Ensenada, Cabo & Mazatlan Cruise

Start:

San Diego, California

End:

San Diego, California

No Port Available

View Full Itinerary

Days:

8

Depart:

8 November 2026

Return:

15 November 2026

Royal Caribbean International

Inside from:

£391

 PP

Outside from:

£394

 PP

Balcony from:

£534

 PP

Cruise & Flights from:

£1,593

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
1 / 0
Serenade of the Seas

7 Night Ensenada, Cabo & La Paz Cruise

Start:

San Diego, California

End:

San Diego, California

No Port Available

View Full Itinerary

Days:

8

Depart:

15 November 2026

Return:

22 November 2026

Royal Caribbean International

Inside from:

£406

 PP

Outside from:

£436

 PP

Balcony from:

£535

 PP

Cruise & Flights from:

£1,541

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine
1 / 0
Serenade of the Seas

7 Night Cabo, Mazatlan & La Paz Cruise

Start:

San Diego, California

End:

San Diego, California

No Port Available

View Full Itinerary

Days:

8

Depart:

22 November 2026

Return:

29 November 2026

Royal Caribbean International

Inside from:

£549

 PP

Outside from:

£624

 PP

Balcony from:

£812

 PP

Cruise & Flights from:

£1,675

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Kids Club (3-17 years old)
Disney entertainment
Waterparks
Adult Only Area
Excellent service & cuisine

Showing 24 out of 108 results