Destination

Any Destination

Date and Duration

Any Date & Duration

Cruise Line

Any Cruise Line

Depart From

Any Departure Port

Panama City, Panama

Expect incredible morning views as you arrive into the port for Panama City. Tinged with a silver pre-dawn light, the city will metamorphosise into a golden glow as the sun rises above it. And from then on expect one stunning view after another. Very interesting in its own right, Fuerte Amador is obviously overshadowed by its proximity to Panama City. So should the Miraflores museum of the Canal, which offers a comprehensive and immersive tour of the Canal including a 3-D experience, four exhibition halls, an observation deck, and a surprisingly good restaurant not interest you then there is always the option of lovely Casco Viejo – literally the old quartier of Panama. The grand old colonial houses, cobbled streets, independent boutiques and buzzing street scene make this a must stop on your itinerary. And if you like seafood, you will not want miss the many restaurants and market stalls serving different variations of so-fresh-it’s-still-practically-swimming ceviche. Best eaten like the Panamanians do, with salty crackers and a cold beer on the beach. And if money is no object, a cup of geisha coffee – supposedly the world’s best and definitely the world’s most expensive at $7 a shot is definitely a pick me up! Cool cosmopolitan capital aside, Panama has a skyscraper filled skyline that is worthy of some of its North American counterparts. But if urban utopia is not your scene then fear not, the sandy beaches and lush rainforests are never more than a short cab ride away.

Cruise Holidays Departing From Panama City, Panama

21 results Found

1 / 0
Oceania Nautica

Canal & Caribbean Discovery

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

11

Depart:

27 January 2026

Return:

6 February 2026

Oceania Cruises

Inside from:

£1,882

 PP

Outside from:

£2,055

 PP

Cruise & Flights from:

£3,382

 PP

1 / 0
Oceania Insignia

Classic Canal & Tropics

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

11

Depart:

4 April 2026

Return:

14 April 2026

Oceania Cruises

Inside from:

£1,942

 PP

Outside from:

£2,115

 PP

Balcony from:

£2,970

 PP

Cruise & Flights from:

£3,502

 PP

1 / 0
Oceania Insignia

Canal & Coral Isles

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

11

Depart:

24 April 2026

Return:

4 May 2026

Oceania Cruises

Inside from:

£1,554

 PP

Outside from:

£1,644

 PP

Balcony from:

£2,376

 PP

Cruise & Flights from:

£3,054

 PP

1 / 0
Oceania Marina

Panama To Caribbean Joy

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

11

Depart:

15 January 2027

Return:

25 January 2027

Oceania Cruises

Inside from:

£2,289

 PP

Outside from:

£2,899

 PP

Balcony from:

£3,429

 PP

Cruise & Flights from:

£3,789

 PP

1 / 0
Seven Seas Grandeur

Journey To The Amazon

Start:

Panama City

End:

Panama City

No Port Available

View Full Itinerary

Days:

23

Depart:

9 March 2027

Return:

31 March 2027

Regent Seven Seas Cruises

Cruise from:

£10,699

 PP

Cruise & Flights from:

£12,144

 PP

1 / 0
Oceania Marina

Panama & Pristine Isles

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

11

Depart:

15 March 2027

Return:

25 March 2027

Oceania Cruises

Inside from:

£2,289

 PP

Outside from:

£2,899

 PP

Balcony from:

£3,429

 PP

Cruise & Flights from:

£3,789

 PP

Award wining dining experience
Small & ultra modern ship
Ocean inspired wellness
Best wellbeing cruise line
Award wining dining experience
Small & ultra modern ship
Ocean inspired wellness
Best wellbeing cruise line
1 / 0
Oceania Marina

Classic Canal & Tropics

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

11

Depart:

16 January 2028

Return:

26 January 2028

Oceania Cruises

Inside from:

£2,359

 PP

Outside from:

£3,119

 PP

Balcony from:

£3,729

 PP

Cruise & Flights from:

£3,799

 PP

1 / 0
Seven Seas Prestige

Bon Bini Aruba

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

13

Depart:

14 March 2028

Return:

26 March 2028

Regent Seven Seas Cruises

Cruise from:

£6,239

 PP

Cruise & Flights from:

£7,304

 PP

1 / 0
Seven Seas Prestige

Azure To Iberia

Start:

Panama City

End:

Lisbon

No Port Available

View Full Itinerary

Days:

27

Depart:

14 March 2028

Return:

9 April 2028

Regent Seven Seas Cruises

Cruise from:

£12,159

 PP

Cruise & Flights from:

£13,019

 PP

1 / 0
Oceania Marina

Spanish Lullaby

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

11

Depart:

15 March 2028

Return:

25 March 2028

Oceania Cruises

Inside from:

£2,289

 PP

Outside from:

£3,049

 PP

Balcony from:

£3,659

 PP

Cruise & Flights from:

£3,729

 PP

Showing 21 out of 21 results