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Panama City, Panama

Expect incredible morning views as you arrive into the port for Panama City. Tinged with a silver pre-dawn light, the city will metamorphosise into a golden glow as the sun rises above it. And from then on expect one stunning view after another. Very interesting in its own right, Fuerte Amador is obviously overshadowed by its proximity to Panama City. So should the Miraflores museum of the Canal, which offers a comprehensive and immersive tour of the Canal including a 3-D experience, four exhibition halls, an observation deck, and a surprisingly good restaurant not interest you then there is always the option of lovely Casco Viejo – literally the old quartier of Panama. The grand old colonial houses, cobbled streets, independent boutiques and buzzing street scene make this a must stop on your itinerary. And if you like seafood, you will not want miss the many restaurants and market stalls serving different variations of so-fresh-it’s-still-practically-swimming ceviche. Best eaten like the Panamanians do, with salty crackers and a cold beer on the beach. And if money is no object, a cup of geisha coffee – supposedly the world’s best and definitely the world’s most expensive at $7 a shot is definitely a pick me up! Cool cosmopolitan capital aside, Panama has a skyscraper filled skyline that is worthy of some of its North American counterparts. But if urban utopia is not your scene then fear not, the sandy beaches and lush rainforests are never more than a short cab ride away.

Cruise Holidays Departing From Panama City, Panama

19 results Found

1 / 0
Oceania Insignia

Classic Canal & Tropics

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

11

Depart:

4 April 2026

Return:

14 April 2026

Oceania Cruises

Inside from:

£2,549

 PP

Outside from:

£2,769

 PP

Cruise & Flights from:

£4,109

 PP

1 / 0
Oceania Insignia

Canal & Coral Isles

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

11

Depart:

24 April 2026

Return:

4 May 2026

Oceania Cruises

Outside from:

£2,769

 PP

Cruise & Flights from:

£4,269

 PP

1 / 0
Oceania Marina

Panama To Caribbean Joy

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

11

Depart:

15 January 2027

Return:

25 January 2027

Oceania Cruises

Inside from:

£2,074

 PP

Outside from:

£2,609

 PP

Balcony from:

£3,085

 PP

Cruise & Flights from:

£3,574

 PP

1 / 0
Seven Seas Grandeur

Journey To The Amazon

Start:

Panama City

End:

Panama City

No Port Available

View Full Itinerary

Days:

23

Depart:

9 March 2027

Return:

31 March 2027

Regent Seven Seas Cruises

Cruise from:

£12,589

 PP

Cruise & Flights from:

£14,034

 PP

1 / 0
Oceania Marina

Panama & Pristine Isles

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

11

Depart:

15 March 2027

Return:

25 March 2027

Oceania Cruises

Inside from:

£2,088

 PP

Outside from:

£2,754

 PP

Balcony from:

£3,096

 PP

Cruise & Flights from:

£3,588

 PP

Award wining dining experience
Small & ultra modern ship
Ocean inspired wellness
Best wellbeing cruise line
Award wining dining experience
Small & ultra modern ship
Ocean inspired wellness
Best wellbeing cruise line
1 / 0
Oceania Marina

Classic Canal & Tropics

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

11

Depart:

16 January 2028

Return:

26 January 2028

Oceania Cruises

Inside from:

£2,359

 PP

Outside from:

£3,119

 PP

Balcony from:

£3,729

 PP

Cruise & Flights from:

£3,799

 PP

1 / 0
Seven Seas Prestige

Azure To Iberia

Start:

Panama City

End:

Lisbon

No Port Available

View Full Itinerary

Days:

27

Depart:

14 March 2028

Return:

9 April 2028

Regent Seven Seas Cruises

Cruise from:

£12,449

 PP

Cruise & Flights from:

£13,529

 PP

1 / 0
Seven Seas Prestige

Bon Bini Aruba

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

13

Depart:

14 March 2028

Return:

26 March 2028

Regent Seven Seas Cruises

Cruise from:

£6,619

 PP

Cruise & Flights from:

£7,904

 PP

1 / 0
Oceania Marina

Spanish Lullaby

Start:

Panama City

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

11

Depart:

15 March 2028

Return:

25 March 2028

Oceania Cruises

Inside from:

£2,289

 PP

Outside from:

£3,049

 PP

Balcony from:

£3,659

 PP

Cruise & Flights from:

£3,729

 PP

Showing 19 out of 19 results