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Lyon, France

Lyon, the capital city in France’s Auvergne-Rhône-Alpes region, sits at the junction of the Rhône and Saône rivers. Its center reflects 2,000 years of history from the Roman Amphithéâtre des Trois Gaules, medieval and Renaissance architecture in Vieux (Old) Lyon, to the modern Confluence district on Presqu'île peninsula. Traboules, covered passageways between buildings, connect Vieux Lyon and La Croix-Rousse hill.

Cruise Holidays Departing From Lyon, France

374 results Found

1 / 0

MS Camargue

Fall Festival: Local History and Traditions on the Rhône River

Start:

Lyon

End:

Lyon

No Port Available

View Full Itinerary

Days:

Depart:

22 March 2026

Return:

25 March 2026

Outside from:

£580

All-Inclusive

Intimate-sized ship

Great Value for Money

English Friendly Cruise Line

1 / 0

MS Mistral

Fall Festival: Local History and Traditions on the Rhône River

Start:

Lyon

End:

Lyon

No Port Available

View Full Itinerary

Days:

Depart:

23 March 2026

Return:

26 March 2026

Outside from:

£538

All-Inclusive

Intimate-sized ship

Great Value for Money

English Friendly Cruise Line

1 / 0

AmaKristina

Colors of Provence (Wine Cruise)

Start:

Lyon

End:

Arles

No Port Available

View Full Itinerary

Days:

Depart:

26 March 2026

Return:

2 April 2026

Balcony from:

£5,818

Cruise & Flights from:

£5,818

All-Included

Immersive guided tours included

Beers, wines and softs included during meals

Flights & transfers inluced

Contemporary small ships

Exceptional service

Award-wining dining

1 / 0

AmaCello

Flavors of Burgundy (Wine Cruise)

Start:

Lyon

End:

Dijon

No Port Available

View Full Itinerary

Days:

Depart:

26 March 2026

Return:

2 April 2026

Outside from:

£4,002

Cruise & Flights from:

£4,002

Balcony from:

£5,156

All-Included

Immersive guided tours included

Beers, wines and softs included during meals

Flights & transfers inluced

Contemporary small ships

Exceptional service

Award-wining dining

1 / 0

Scenic Sapphire

Spectacular South of France

Start:

Lyon

End:

Lyon

No Port Available

View Full Itinerary

Days:

Depart:

27 March 2026

Return:

6 April 2026

Outside from:

£3,895

Cruise & Flights from:

£3,895

1 / 0

S.S. Catherine

Burgundy & Provence

Start:

Lyon

End:

Arles

No Port Available

View Full Itinerary

Days:

Depart:

29 March 2026

Return:

5 April 2026

Outside from:

£3,165

Cruise & Flights from:

£3,165

Balcony from:

£3,665

1 / 0

MS Van Gogh

Fall Festival: Local History and Traditions on the Rhône River

Start:

Lyon

End:

Lyon

No Port Available

View Full Itinerary

Days:

Depart:

1 April 2026

Return:

4 April 2026

Outside from:

£756

All-Inclusive

Intimate-sized ship

Great Value for Money

English Friendly Cruise Line

1 / 0

MS Thomas Hardy

History and Art of the Rhône River Cruise - MS Thomas Hardy

Start:

Lyon

End:

Avignon

No Port Available

View Full Itinerary

Days:

Depart:

3 April 2026

Return:

10 April 2026

Cruise & Flights from:

£1,899

1 / 0

MS Camargue

All the must-see sites on the Rhône between Lyon, Provence, and the Camargue with a dinner at Paul Bocuse's Abbaye de Collonges Restaurant OFFERED (port-to-port cruise)

Start:

Lyon

End:

Lyon

No Port Available

View Full Itinerary

Days:

Depart:

5 April 2026

Return:

10 April 2026

Outside from:

£1,458

All-Inclusive

Intimate-sized ship

Great Value for Money

English Friendly Cruise Line

1 / 0

Scenic Sapphire

Spectacular South of France

Start:

Lyon

End:

Lyon

No Port Available

View Full Itinerary

Days:

Depart:

6 April 2026

Return:

16 April 2026

Outside from:

£3,983

Cruise & Flights from:

£3,983

1 / 0

MS Rhone Princess

From Burgundy to the Camargue along the Saône and the Rhône Rivers (port-to-port cruise)

Start:

Lyon

End:

Lyon

No Port Available

View Full Itinerary

Days:

Depart:

6 April 2026

Return:

12 April 2026

Outside from:

£1,354

All-Inclusive

Intimate-sized ship

Great Value for Money

English Friendly Cruise Line

1 / 0

MS Rhone Princess

Cruise and Hikes: The Rhône and the Saône Reveal the Richness of Their Terroirs (port-to-port cruise)

Start:

Lyon

End:

Lyon

No Port Available

View Full Itinerary

Days:

Depart:

6 April 2026

Return:

13 April 2026

Outside from:

£1,753

All-Inclusive

Intimate-sized ship

Great Value for Money

English Friendly Cruise Line

1 / 0

MS Lord Byron

Gardens and Natural Beauty of the Rhône River Cruise - MS Lord Byron

Start:

Lyon

End:

Avignon

No Port Available

View Full Itinerary

Days:

Depart:

8 April 2026

Return:

15 April 2026

Outside from:

£1,949

Cruise & Flights from:

£1,949

1 / 0

AmaKristina

Colors of Provence (Wine Cruise)

Start:

Lyon

End:

Arles

No Port Available

View Full Itinerary

Days:

Depart:

9 April 2026

Return:

16 April 2026

Balcony from:

£5,863

Cruise & Flights from:

£5,863

All-Included

Immersive guided tours included

Beers, wines and softs included during meals

Flights & transfers inluced

Contemporary small ships

Exceptional service

Award-wining dining

1 / 0

MS Thomas Hardy

Lyon, Provençal Rhône & the Camargue River Cruise - MS Thomas Hardy

Start:

Lyon

End:

Lyon

No Port Available

View Full Itinerary

Days:

Depart:

10 April 2026

Return:

20 April 2026

Cruise & Flights from:

£2,949

1 / 0

S.S. Catherine

Burgundy & Provence

Start:

Lyon

End:

Arles

No Port Available

View Full Itinerary

Days:

Depart:

12 April 2026

Return:

19 April 2026

Outside from:

£4,799

Cruise & Flights from:

£4,799

Balcony from:

£6,249

1 / 0

MS Camargue

From Burgundy to the Camargue along the Saône and the Rhône Rivers (port-to-port cruise)

Start:

Lyon

End:

Lyon

No Port Available

View Full Itinerary

Days:

Depart:

16 April 2026

Return:

22 April 2026

Outside from:

£1,614

All-Inclusive

Intimate-sized ship

Great Value for Money

English Friendly Cruise Line

1 / 0

MS Van Gogh

All the must-see sites on the Rhône between Lyon, Provence, and the Camargue with a dinner at Paul Bocuse's Abbaye de Collonges Restaurant OFFERED (port-to-port cruise)

Start:

Lyon

End:

Lyon

No Port Available

View Full Itinerary

Days:

Depart:

16 April 2026

Return:

21 April 2026

Outside from:

£1,458

All-Inclusive

Intimate-sized ship

Great Value for Money

English Friendly Cruise Line

1 / 0

MS Camargue

Art and History along the Rhône (port-to-port cruise)

Start:

Lyon

End:

Lyon

No Port Available

View Full Itinerary

Days:

Depart:

16 April 2026

Return:

22 April 2026

Outside from:

£2,061

All-Inclusive

Intimate-sized ship

Great Value for Money

English Friendly Cruise Line

1 / 0

Riverside Ravel

Snapshot of the Rhône With Châteauneuf-du-Pape

Start:

Lyon

End:

Châteauneuf-du-Pape

No Port Available

View Full Itinerary

Days:

Depart:

19 April 2026

Return:

23 April 2026

Cruise from:

£3,062

1 / 0

Riverside Ravel

Rhône River Roaming With Rhône Delta & Pont du Gard

Start:

Lyon

End:

Avignon

No Port Available

View Full Itinerary

Days:

Depart:

19 April 2026

Return:

26 April 2026

Cruise from:

£4,868

1 / 0

MS Lord Byron

Lyon, Provençal Rhône & the Camargue River Cruise - MS Lord Byron

Start:

Lyon

End:

Lyon

No Port Available

View Full Itinerary

Days:

Depart:

22 April 2026

Return:

2 May 2026

Outside from:

£3,049

Cruise & Flights from:

£3,049

1 / 0

AmaCello

Flavors of Burgundy (Wine Cruise)

Start:

Lyon

End:

Dijon

No Port Available

View Full Itinerary

Days:

Depart:

23 April 2026

Return:

30 April 2026

Outside from:

£5,325

Cruise & Flights from:

£5,325

Balcony from:

£6,479

All-Included

Immersive guided tours included

Beers, wines and softs included during meals

Flights & transfers inluced

Contemporary small ships

Exceptional service

Award-wining dining

1 / 0

MS Camargue

All the must-see sites on the Rhône between Lyon, Provence, and the Camargue with a dinner at Paul Bocuse's Abbaye de Collonges Restaurant OFFERED (port-to-port cruise)

Start:

Lyon

End:

Lyon

No Port Available

View Full Itinerary

Days:

Depart:

23 April 2026

Return:

28 April 2026

Outside from:

£1,705

All-Inclusive

Intimate-sized ship

Great Value for Money

English Friendly Cruise Line

Showing 24 out of 374 results

Navigation

Lyon, France

Cruise Holidays Departing From Lyon, France

374 results Found

Fall Festival: Local History and Traditions on the Rhône River

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End:

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Depart:

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Outside from:

Fall Festival: Local History and Traditions on the Rhône River

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Days:

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Return:

Outside from:

Colors of Provence (Wine Cruise)

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Days:

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Balcony from:

Cruise & Flights from:

Flavors of Burgundy (Wine Cruise)

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Cruise & Flights from:

Balcony from:

Spectacular South of France

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Days:

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Return:

Outside from:

Cruise & Flights from:

Burgundy & Provence

Start:

End:

Days:

Depart:

Return:

Outside from:

Cruise & Flights from:

Balcony from:

Fall Festival: Local History and Traditions on the Rhône River

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End:

Days:

Depart:

Return:

Outside from:

History and Art of the Rhône River Cruise - MS Thomas Hardy

Start:

End:

Days:

Depart:

Return:

Cruise & Flights from:

All the must-see sites on the Rhône between Lyon, Provence, and the Camargue with a dinner at Paul Bocuse's Abbaye de Collonges Restaurant OFFERED (port-to-port cruise)

Start:

End:

Days:

Depart:

Return:

Outside from:

Spectacular South of France

Start:

End:

Days:

Depart:

Return:

Outside from: