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Colón, Panama

The provincial capital of Colón, beside the canal's Atlantic entrance, is named for the Spanish-language surname of Christopher Columbus, though the Americans called it Aspinwall in the 19th century.. The city was founded in 1850 by Americans working on the Panama railroad and named Aspinwall for one of the railway engineers. Following completion in 1855, Colon gained in importance, which was furthered by the plans for an isthmian canal. During the time of the French canal attempt, a fire in 1885 burned the city nearly to the ground and left thousands of people homeless. Colon was rebuilt in the architectural style then popular in France. Buildings from that era plus the ones constructed by Americans between 1904 and 1914 are still in use today, although the majority is on the verge of collapse. In addition to its importance as a port, Colon boasts the world’s second largest duty-free zone, known as Zona Libre, which is contained in a huge fortress like, walled-off area with giant international stores. However, most of the merchandise is sold in bulk to commercial businesses throughout the country.

Cruise Holidays Departing From Colón, Panama

106 results Found

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

21 March 2026

Return:

28 March 2026

Royal Caribbean International

Inside from:

£851

 PP

Outside from:

£851

 PP

Balcony from:

£1,180

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Hand crafted itinerary
French Gastronomy curated by World Class chef
All Included
Intimate ships
Luxury expedition
French & English cruise Line
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

28 March 2026

Return:

4 April 2026

Royal Caribbean International

Inside from:

£1,056

 PP

Cruise & Flights from:

£2,240

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

11 April 2026

Return:

18 April 2026

Royal Caribbean International

Inside from:

£930

 PP

Outside from:

£964

 PP

Balcony from:

£1,050

 PP

Cruise & Flights from:

£1,829

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

1 Night Southern Caribbean Cruise

Start:

Colón

End:

Cartagena

No Port Available

View Full Itinerary

Days:

2

Depart:

18 April 2026

Return:

19 April 2026

Royal Caribbean International

Inside from:

£107

 PP

Outside from:

£110

 PP

Balcony from:

£139

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

10 Night Panama Canal Westward Cruise

Start:

Colón

End:

Los Angeles, California

No Port Available

View Full Itinerary

Days:

11

Depart:

25 April 2026

Return:

5 May 2026

Royal Caribbean International

Inside from:

£624

 PP

Outside from:

£701

 PP

Balcony from:

£1,236

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

9 May 2026

Return:

16 May 2026

Royal Caribbean International

Inside from:

£686

 PP

Outside from:

£936

 PP

Balcony from:

£1,295

 PP

Cruise & Flights from:

£1,593

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

16 May 2026

Return:

23 May 2026

Royal Caribbean International

Inside from:

£620

 PP

Outside from:

£657

 PP

Balcony from:

£1,200

 PP

Cruise & Flights from:

£1,519

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

23 May 2026

Return:

30 May 2026

Royal Caribbean International

Inside from:

£876

 PP

Outside from:

£1,178

 PP

Balcony from:

£1,302

 PP

Cruise & Flights from:

£1,783

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

30 May 2026

Return:

6 June 2026

Royal Caribbean International

Inside from:

£547

 PP

Outside from:

£554

 PP

Balcony from:

£972

 PP

Cruise & Flights from:

£1,454

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

6 June 2026

Return:

13 June 2026

Royal Caribbean International

Inside from:

£636

 PP

Outside from:

£644

 PP

Balcony from:

£915

 PP

Cruise & Flights from:

£1,672

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

13 June 2026

Return:

20 June 2026

Royal Caribbean International

Inside from:

£930

 PP

Outside from:

£974

 PP

Balcony from:

£1,039

 PP

Cruise & Flights from:

£1,959

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

20 June 2026

Return:

27 June 2026

Royal Caribbean International

Inside from:

£614

 PP

Outside from:

£666

 PP

Balcony from:

£885

 PP

Cruise & Flights from:

£1,651

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

27 June 2026

Return:

4 July 2026

Royal Caribbean International

Inside from:

£619

 PP

Outside from:

£690

 PP

Balcony from:

£885

 PP

Cruise & Flights from:

£1,546

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

4 July 2026

Return:

11 July 2026

Royal Caribbean International

Inside from:

£745

 PP

Outside from:

£782

 PP

Balcony from:

£979

 PP

Cruise & Flights from:

£1,680

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

11 July 2026

Return:

18 July 2026

Royal Caribbean International

Inside from:

£767

 PP

Outside from:

£862

 PP

Balcony from:

£899

 PP

Cruise & Flights from:

£1,674

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

18 July 2026

Return:

25 July 2026

Royal Caribbean International

Inside from:

£657

 PP

Outside from:

£756

 PP

Balcony from:

£1,248

 PP

Cruise & Flights from:

£1,592

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

25 July 2026

Return:

1 August 2026

Royal Caribbean International

Inside from:

£745

 PP

Outside from:

£752

 PP

Balcony from:

£987

 PP

Cruise & Flights from:

£1,637

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

1 August 2026

Return:

8 August 2026

Royal Caribbean International

Outside from:

£749

 PP

Inside from:

£797

 PP

Balcony from:

£1,054

 PP

Cruise & Flights from:

£1,641

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

8 August 2026

Return:

15 August 2026

Royal Caribbean International

Inside from:

£701

 PP

Outside from:

£819

 PP

Balcony from:

£1,060

 PP

Cruise & Flights from:

£1,593

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

15 August 2026

Return:

22 August 2026

Royal Caribbean International

Inside from:

£760

 PP

Outside from:

£774

 PP

Balcony from:

£1,036

 PP

Cruise & Flights from:

£1,688

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Grandeur of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

22 August 2026

Return:

29 August 2026

Royal Caribbean International

Inside from:

£686

 PP

Outside from:

£737

 PP

Balcony from:

£987

 PP

Cruise & Flights from:

£1,614

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board

Showing 24 out of 106 results