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Colón, Panama

The provincial capital of Colón, beside the canal's Atlantic entrance, is named for the Spanish-language surname of Christopher Columbus, though the Americans called it Aspinwall in the 19th century.. The city was founded in 1850 by Americans working on the Panama railroad and named Aspinwall for one of the railway engineers. Following completion in 1855, Colon gained in importance, which was furthered by the plans for an isthmian canal. During the time of the French canal attempt, a fire in 1885 burned the city nearly to the ground and left thousands of people homeless. Colon was rebuilt in the architectural style then popular in France. Buildings from that era plus the ones constructed by Americans between 1904 and 1914 are still in use today, although the majority is on the verge of collapse. In addition to its importance as a port, Colon boasts the world’s second largest duty-free zone, known as Zona Libre, which is contained in a huge fortress like, walled-off area with giant international stores. However, most of the merchandise is sold in bulk to commercial businesses throughout the country.

Cruise Holidays Departing From Colón, Panama

111 results Found

Hand crafted itinerary
French Gastronomy curated by World Class chef
All Included
Intimate ships
Luxury expedition
French & English cruise Line
1 / 0
Serenade of the Seas

8 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

9

Depart:

12 December 2025

Return:

20 December 2025

Royal Caribbean International

Inside from:

£844

 PP

Outside from:

£882

 PP

Balcony from:

£918

 PP

Cruise & Flights from:

£2,019

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Hand crafted itinerary
French Gastronomy curated by World Class chef
All Included
Intimate ships
Luxury expedition
French & English cruise Line
Hand crafted itinerary
French Gastronomy curated by World Class chef
All Included
Intimate ships
Luxury expedition
French & English cruise Line
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

3 January 2026

Return:

10 January 2026

Royal Caribbean International

Balcony from:

£899

 PP

Outside from:

£954

 PP

Inside from:

£976

 PP

Cruise & Flights from:

£2,609

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

10 January 2026

Return:

17 January 2026

Royal Caribbean International

Inside from:

£844

 PP

Outside from:

£844

 PP

Balcony from:

£880

 PP

Cruise & Flights from:

£2,053

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Hand crafted itinerary
French Gastronomy curated by World Class chef
All Included
Intimate ships
Luxury expedition
French & English cruise Line
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

17 January 2026

Return:

24 January 2026

Royal Caribbean International

Balcony from:

£764

 PP

Outside from:

£901

 PP

Cruise & Flights from:

£1,840

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Hand crafted itinerary
French Gastronomy curated by World Class chef
All Included
Intimate ships
Luxury expedition
French & English cruise Line
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

24 January 2026

Return:

31 January 2026

Royal Caribbean International

Outside from:

£715

 PP

Balcony from:

£750

 PP

Cruise & Flights from:

£1,687

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

31 January 2026

Return:

7 February 2026

Royal Caribbean International

Outside from:

£752

 PP

Balcony from:

£772

 PP

Inside from:

£827

 PP

Cruise & Flights from:

£1,716

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

7 February 2026

Return:

14 February 2026

Royal Caribbean International

Balcony from:

£832

 PP

Outside from:

£842

 PP

Cruise & Flights from:

£1,827

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

14 February 2026

Return:

21 February 2026

Royal Caribbean International

Outside from:

£891

 PP

Balcony from:

£933

 PP

Cruise & Flights from:

£1,899

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Hand crafted itinerary
French Gastronomy curated by World Class chef
All Included
Intimate ships
Luxury expedition
French & English cruise Line
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

21 February 2026

Return:

28 February 2026

Royal Caribbean International

Inside from:

£818

 PP

Outside from:

£818

 PP

Balcony from:

£854

 PP

Cruise & Flights from:

£1,819

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board

Showing 24 out of 111 results