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Colón, Panama

The provincial capital of Colón, beside the canal's Atlantic entrance, is named for the Spanish-language surname of Christopher Columbus, though the Americans called it Aspinwall in the 19th century.. The city was founded in 1850 by Americans working on the Panama railroad and named Aspinwall for one of the railway engineers. Following completion in 1855, Colon gained in importance, which was furthered by the plans for an isthmian canal. During the time of the French canal attempt, a fire in 1885 burned the city nearly to the ground and left thousands of people homeless. Colon was rebuilt in the architectural style then popular in France. Buildings from that era plus the ones constructed by Americans between 1904 and 1914 are still in use today, although the majority is on the verge of collapse. In addition to its importance as a port, Colon boasts the world’s second largest duty-free zone, known as Zona Libre, which is contained in a huge fortress like, walled-off area with giant international stores. However, most of the merchandise is sold in bulk to commercial businesses throughout the country.

Cruise Holidays Departing From Colón, Panama

118 results Found

Hand crafted itinerary
French Gastronomy curated by World Class chef
All Included
Intimate ships
Luxury expedition
French & English cruise Line
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Hand crafted itinerary
French Gastronomy curated by World Class chef
All Included
Intimate ships
Luxury expedition
French & English cruise Line
Hand crafted itinerary
French Gastronomy curated by World Class chef
All Included
Intimate ships
Luxury expedition
French & English cruise Line
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

31 January 2026

Return:

7 February 2026

Royal Caribbean International

Inside from:

£827

 PP

Outside from:

£827

 PP

Balcony from:

£848

 PP

Cruise & Flights from:

£1,867

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

7 February 2026

Return:

14 February 2026

Royal Caribbean International

Balcony from:

£822

 PP

Outside from:

£832

 PP

Cruise & Flights from:

£1,870

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

14 February 2026

Return:

21 February 2026

Royal Caribbean International

Balcony from:

£1,081

 PP

Inside from:

£1,082

 PP

Outside from:

£1,082

 PP

Cruise & Flights from:

£2,129

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

21 February 2026

Return:

28 February 2026

Royal Caribbean International

Inside from:

£849

 PP

Outside from:

£849

 PP

Balcony from:

£886

 PP

Cruise & Flights from:

£1,764

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

28 February 2026

Return:

7 March 2026

Royal Caribbean International

Inside from:

£800

 PP

Outside from:

£832

 PP

Balcony from:

£962

 PP

Cruise & Flights from:

£1,800

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

7 March 2026

Return:

14 March 2026

Royal Caribbean International

Inside from:

£782

 PP

Outside from:

£790

 PP

Balcony from:

£865

 PP

Cruise & Flights from:

£1,789

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

14 March 2026

Return:

21 March 2026

Royal Caribbean International

Inside from:

£753

 PP

Outside from:

£753

 PP

Balcony from:

£767

 PP

Cruise & Flights from:

£1,873

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

21 March 2026

Return:

28 March 2026

Royal Caribbean International

Inside from:

£944

 PP

Outside from:

£944

 PP

Balcony from:

£1,073

 PP

Cruise & Flights from:

£2,185

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Hand crafted itinerary
French Gastronomy curated by World Class chef
All Included
Intimate ships
Luxury expedition
French & English cruise Line
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

28 March 2026

Return:

4 April 2026

Royal Caribbean International

Inside from:

£755

 PP

Outside from:

£794

 PP

Balcony from:

£862

 PP

Cruise & Flights from:

£1,906

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

4 April 2026

Return:

11 April 2026

Royal Caribbean International

Inside from:

£661

 PP

Balcony from:

£1,141

 PP

Cruise & Flights from:

£1,828

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

7 Night Southern Caribbean Cruise

Start:

Colón

End:

Colón

No Port Available

View Full Itinerary

Days:

8

Depart:

11 April 2026

Return:

18 April 2026

Royal Caribbean International

Inside from:

£744

 PP

Outside from:

£797

 PP

Balcony from:

£871

 PP

Cruise & Flights from:

£1,665

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

1 Night Southern Caribbean Cruise

Start:

Colón

End:

Cartagena

No Port Available

View Full Itinerary

Days:

2

Depart:

18 April 2026

Return:

19 April 2026

Royal Caribbean International

Outside from:

£107

 PP

Balcony from:

£137

 PP

Cruise & Flights from:

£2,427

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Serenade of the Seas

10 Night Panama Canal Westward Cruise

Start:

Colón

End:

Los Angeles, California

No Port Available

View Full Itinerary

Days:

11

Depart:

25 April 2026

Return:

5 May 2026

Royal Caribbean International

Inside from:

£672

 PP

Outside from:

£815

 PP

Balcony from:

£1,301

 PP

Cruise & Flights from:

£1,440

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board

Showing 24 out of 118 results