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Cape Town, South Africa

Sometimes referred to as the Mother City, Cape Town is the most famous port in South Africa and is influenced by many different cultures, including Dutch, British and Malay. The port was founded in 1652 by Dutch explorer Jan Van Riebeeck, and evidence of Dutch colonial rule remains throughout the region. The port is located on one of the world's most important trade routes, and is mainly a container port and handler of fresh fruit. Fishing is another vital industry, with large Asian fishing fleets using Cape Town as a logistical repair base for much of the year. The region is famous for its natural beauty, with the imposing Table Mountain and Lions Head, as well as the many nature reserves and botanical gardens such as Kirstenbosch which boasts an extensive range of indigenous plant life, including proteas and ferns. Cape Town's weather is mercurial, and can change from beautiful sunshine to dramatic thunderstorms within a short period. A local adage is that in Cape Town you can experience four seasons in one day.

Cruise Holidays Departing From Cape Town, South Africa

103 results Found

All-Included
Immersive guided tours included
Beers, wines and softs included during meals
Flights & transfers inluced
Contemporary small ships
Exceptional service
Award-wining dining
All-Included
Immersive guided tours included
Beers, wines and softs included during meals
Flights & transfers inluced
Contemporary small ships
Exceptional service
Award-wining dining
1 / 0
Zambezi Queen

Discover Africa

Start:

Cape Town

End:

Victoria Falls

No Port Available

View Full Itinerary

Days:

9

Depart:

31 October 2025

Return:

9 November 2025

AmaWaterways

Balcony from:

£11,058

 PP

Cruise & Flights from:

£11,058

 PP

All-Included
Immersive guided tours included
Beers, wines and softs included during meals
Flights & transfers inluced
Contemporary small ships
Exceptional service
Award-wining dining
All Included
Extended Destination Days
Exclusive cultural events included
Small, intimate ships with a cosy and stylish design
All Included
Extended Destination Days
Exclusive cultural events included
Small, intimate ships with a cosy and stylish design
1 / 0
Oceania Sirena

Indian Ocean Opus

Start:

Cape Town

End:

Singapore

No Port Available

View Full Itinerary

Days:

25

Depart:

2 December 2025

Return:

26 December 2025

Oceania Cruises

Inside from:

£4,484

 PP

Outside from:

£4,988

 PP

Cruise & Flights from:

£6,444

 PP

Balcony from:

£6,507

 PP

1 / 0
Seven Seas Voyager

Shores Of Madagascar

Start:

Cape Town

End:

Port Louis

No Port Available

View Full Itinerary

Days:

17

Depart:

27 January 2026

Return:

12 February 2026

Regent Seven Seas Cruises

Cruise from:

£8,849

 PP

Cruise & Flights from:

£10,149

 PP

Last true ocean liner
Elegance and tradition of cruising
Kids Club (2-17 years old)
Lot of specialty restaurants
Last true ocean liner
Elegance and tradition of cruising
Kids Club (2-17 years old)
Lot of specialty restaurants
Last true ocean liner
Elegance and tradition of cruising
Kids Club (2-17 years old)
Lot of specialty restaurants
All Included
Extended Destination Days
Exclusive cultural events included
Small, intimate ships with a cosy and stylish design
1 / 0
Seven Seas Voyager

West African Adventure

Start:

Cape Town

End:

Lisbon

No Port Available

View Full Itinerary

Days:

24

Depart:

28 February 2026

Return:

23 March 2026

Regent Seven Seas Cruises

Cruise from:

£10,349

 PP

Cruise & Flights from:

£11,609

 PP

Hand crafted itinerary
French Gastronomy curated by World Class chef
All Included
Intimate ships
Luxury expedition
French & English cruise Line
Personalised service (1/1 guest-to-crew ratio)
All-inclusive
Gourmet dining
Small and intimate ships
Lectures onboard
Champagne & butler service for all cabins
1 / 0
Oceania Sirena

African Revelation

Start:

Cape Town

End:

Lisbon

No Port Available

View Full Itinerary

Days:

25

Depart:

31 March 2026

Return:

24 April 2026

Oceania Cruises

Inside from:

£4,730

 PP

Outside from:

£5,045

 PP

Cruise & Flights from:

£6,260

 PP

Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
1 / 0
Queen Mary 2

Cape Town to New York

Start:

Cape Town

End:

New York, New York

No Port Available

View Full Itinerary

Days:

26

Depart:

13 April 2026

Return:

8 May 2026

Cunard

Inside from:

£3,189

 PP

Cruise & Flights from:

£4,389

 PP

Outside from:

£4,449

 PP

Balcony from:

£4,779

 PP

Last true ocean liner
Elegance and tradition of cruising
Kids Club (2-17 years old)
Lot of specialty restaurants
1 / 0
Queen Mary 2

Cape Town to Southampton

Start:

Cape Town

End:

Southampton

No Port Available

View Full Itinerary

Days:

18

Depart:

13 April 2026

Return:

30 April 2026

Cunard

Outside from:

£2,399

 PP

Balcony from:

£2,949

 PP

Cruise & Flights from:

£3,159

 PP

Last true ocean liner
Elegance and tradition of cruising
Kids Club (2-17 years old)
Lot of specialty restaurants
Personalised service (1/1 guest-to-crew ratio)
All-inclusive
Gourmet dining
Small and intimate ships
Lectures onboard
Champagne & butler service for all cabins
1 / 0
Seven Seas Mariner

Western Africa & Isles Of Wonder

Start:

Cape Town

End:

Lisbon

No Port Available

View Full Itinerary

Days:

25

Depart:

9 May 2026

Return:

2 June 2026

Regent Seven Seas Cruises

Cruise from:

£12,239

 PP

Cruise & Flights from:

£13,004

 PP

1 / 0
Norwegian Sun

Africa: Spain, Canary Islands & Namibia

Start:

Cape Town

End:

Southampton

No Port Available

View Full Itinerary

Days:

23

Depart:

10 May 2026

Return:

1 June 2026

Norwegian Cruise Line

Inside from:

£4,219

 PP

Outside from:

£4,414

 PP

Balcony from:

£7,138

 PP

Showing 24 out of 103 results