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South America

Raw Nature & Ancient Civilisations

Embark on an extraordinary cruise through South America, a land of striking contrasts where wildlife, dramatic landscapes and archaeological treasures come together at every stop.

Sail to the Galápagos Islands, a UNESCO-listed natural sanctuary, where you’ll encounter marine iguanas, giant tortoises, sea lions and rare birds in an untouched volcanic setting.
In Peru, immerse yourself in the rich legacy of pre-Columbian cultures and explore fascinating archaeological sites nestled between the Pacific Ocean and the Andes.
Along the Chilean coast, marvel at hidden fjords, towering glaciers and scenic terraced vineyards, and soak up the vibrant atmosphere of Valparaíso or the peaceful charm of southern Patagonian villages.

When is the best time to cruise South America?

The best time to explore South America's coastline by cruise is from October to April, offering ideal conditions to sail through Patagonia, Chile and Peru.
The Galápagos Islands can be visited year-round, with warmer weather from December to May, and a cooler, drier season from June to November.

Cruise Holidays to South America

1,112 results Found

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
MSC Fantasia

Uruguay, Argentina, Brazil

Start:

Montevideo

End:

Montevideo

No Port Available

View Full Itinerary

Days:

9

Depart:

9 December 2025

Return:

17 December 2025

MSC Cruises

Inside from:

£839

 PP

Outside from:

£1,031

 PP

Balcony from:

£1,127

 PP

Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
1 / 0
MSC Fantasia

Uruguay, Argentina, Brazil

Start:

Montevideo

End:

Montevideo

No Port Available

View Full Itinerary

Days:

9

Depart:

17 December 2025

Return:

25 December 2025

MSC Cruises

Inside from:

£1,043

 PP

Outside from:

£1,223

 PP

Balcony from:

£1,403

 PP

Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
1 / 0
MSC Fantasia

Argentina, Brazil, Uruguay

Start:

Buenos Aires

End:

Buenos Aires

No Port Available

View Full Itinerary

Days:

9

Depart:

18 December 2025

Return:

26 December 2025

MSC Cruises

Inside from:

£1,043

 PP

Outside from:

£1,295

 PP

Balcony from:

£1,403

 PP

Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
1 / 0
MSC Seaview

Santos, Buzios, Salvador, Maceio, Santos

Start:

Santos

End:

Santos

No Port Available

View Full Itinerary

Days:

8

Depart:

19 December 2025

Return:

26 December 2025

MSC Cruises

Inside from:

£1,117

 PP

Outside from:

£1,260

 PP

Balcony from:

£1,404

 PP

Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark

Showing 24 out of 1112 results