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South America

Raw Nature & Ancient Civilisations

Embark on an extraordinary cruise through South America, a land of striking contrasts where wildlife, dramatic landscapes and archaeological treasures come together at every stop.

Sail to the Galápagos Islands, a UNESCO-listed natural sanctuary, where you’ll encounter marine iguanas, giant tortoises, sea lions and rare birds in an untouched volcanic setting.
In Peru, immerse yourself in the rich legacy of pre-Columbian cultures and explore fascinating archaeological sites nestled between the Pacific Ocean and the Andes.
Along the Chilean coast, marvel at hidden fjords, towering glaciers and scenic terraced vineyards, and soak up the vibrant atmosphere of Valparaíso or the peaceful charm of southern Patagonian villages.

When is the best time to cruise South America?

The best time to explore South America's coastline by cruise is from October to April, offering ideal conditions to sail through Patagonia, Chile and Peru.
The Galápagos Islands can be visited year-round, with warmer weather from December to May, and a cooler, drier season from June to November.

Cruise Holidays to South America

885 results Found

1 / 0
Quantum of the Seas

6 Night Cabo Overnight And Ensenada

Start:

Los Angeles, California

End:

Los Angeles, California

No Port Available

View Full Itinerary

Days:

7

Depart:

15 April 2026

Return:

21 April 2026

Royal Caribbean International

Inside from:

£473

 PP

Outside from:

£721

 PP

Balcony from:

£757

 PP

Cruise & Flights from:

£1,263

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Adults -Only
Modern & Futuristic Ship Design
Fun, laid-back atmosphere
Exceptional dining
Immersive and interactive shows
All-Included
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Quantum of the Seas

7 Night Cabo Overnight & Ensenada

Start:

Los Angeles, California

End:

Los Angeles, California

No Port Available

View Full Itinerary

Days:

8

Depart:

1 May 2026

Return:

8 May 2026

Royal Caribbean International

Inside from:

£473

 PP

Outside from:

£508

 PP

Cruise & Flights from:

£1,297

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Navigator of the Seas

7 Night Ensenada, Cabo & Mazatlan

Start:

Los Angeles, California

End:

Los Angeles, California

No Port Available

View Full Itinerary

Days:

8

Depart:

1 May 2026

Return:

8 May 2026

Royal Caribbean International

Inside from:

£366

 PP

Balcony from:

£616

 PP

Cruise & Flights from:

£1,190

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Navigator of the Seas

7 Night Cabo, Vallarta & Mazatlan

Start:

Los Angeles, California

End:

Los Angeles, California

No Port Available

View Full Itinerary

Days:

8

Depart:

8 May 2026

Return:

15 May 2026

Royal Caribbean International

Inside from:

£385

 PP

Balcony from:

£804

 PP

Outside from:

£855

 PP

Cruise & Flights from:

£1,226

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Quantum of the Seas

3 Night Ensenada Cruise

Start:

Los Angeles, California

End:

Los Angeles, California

No Port Available

View Full Itinerary

Days:

4

Depart:

8 May 2026

Return:

11 May 2026

Royal Caribbean International

Inside from:

£319

 PP

Outside from:

£339

 PP

Balcony from:

£381

 PP

Cruise & Flights from:

£1,160

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Resilient Lady

Mexico & Bimini Beach Club

Start:

Miami, Florida

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

6

Depart:

11 May 2026

Return:

16 May 2026

Virgin Voyages

Inside from:

£553

 PP

Outside from:

£609

 PP

Balcony from:

£685

 PP

Adults -Only
Modern & Futuristic Ship Design
Fun, laid-back atmosphere
Exceptional dining
Immersive and interactive shows
All-Included
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Quantum of the Seas

4 Night Catalina & Ensenada Cruise

Start:

Los Angeles, California

End:

Los Angeles, California

No Port Available

View Full Itinerary

Days:

5

Depart:

1 June 2026

Return:

5 June 2026

Royal Caribbean International

Inside from:

£351

 PP

Outside from:

£388

 PP

Balcony from:

£458

 PP

Cruise & Flights from:

£1,543

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board

Showing 24 out of 885 results