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South America

Raw Nature & Ancient Civilisations

Embark on an extraordinary cruise through South America, a land of striking contrasts where wildlife, dramatic landscapes and archaeological treasures come together at every stop.

Sail to the Galápagos Islands, a UNESCO-listed natural sanctuary, where you’ll encounter marine iguanas, giant tortoises, sea lions and rare birds in an untouched volcanic setting.
In Peru, immerse yourself in the rich legacy of pre-Columbian cultures and explore fascinating archaeological sites nestled between the Pacific Ocean and the Andes.
Along the Chilean coast, marvel at hidden fjords, towering glaciers and scenic terraced vineyards, and soak up the vibrant atmosphere of Valparaíso or the peaceful charm of southern Patagonian villages.

When is the best time to cruise South America?

The best time to explore South America's coastline by cruise is from October to April, offering ideal conditions to sail through Patagonia, Chile and Peru.
The Galápagos Islands can be visited year-round, with warmer weather from December to May, and a cooler, drier season from June to November.

Cruise Holidays to South America

1,098 results Found

Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
1 / 0
Oceania Insignia

Call Of The Amazon

Start:

Miami, Florida

End:

Miami, Florida

No Port Available

View Full Itinerary

Days:

26

Depart:

12 November 2025

Return:

7 December 2025

Oceania Cruises

Inside from:

£5,329

 PP

Outside from:

£5,859

 PP

Cruise & Flights from:

£6,529

 PP

Balcony from:

£8,749

 PP

Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Elegant & mid-size ships
Award wining excursions
Excellent cuisine
Extended destination days
Kids Club (3-17 years old)
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Elegant & mid-size ships
Award wining excursions
Excellent cuisine
Extended destination days
Kids Club (3-17 years old)
1 / 0
MSC Fantasia

Uruguay, Argentina, Brazil

Start:

Montevideo

End:

Montevideo

No Port Available

View Full Itinerary

Days:

9

Depart:

23 November 2025

Return:

1 December 2025

MSC Cruises

Inside from:

£731

 PP

Outside from:

£911

 PP

Balcony from:

£1,175

 PP

Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Innovative ships packed with endless activities
Reduced child fare
Perfect for families and activity-seekers
Excellent dining and attentive service
Aqua Theater and/or Ice rink on board
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark
Lot of Activities
Great Value for Money
Reduced child fares
Kids Club (0-17 years old)
Aquapark

Showing 24 out of 1098 results